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Oxidation polymorphism of sparteine in patients with parkinsonism

✍ Scribed by Imai, Hisamasa; Yoshino, Hideo; Narabayashi, Hirotaro; Chiba, Kan

Book ID
123064787
Publisher
Elsevier Science
Year
1989
Weight
68 KB
Volume
9
Category
Article
ISSN
0921-8696

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The genetic oxidation polymorphism was determined in 160 healthy Polish volunteers from the southwest of Poland (Wroctaw region), using sparteine as a model drug. The results of a Polish population study revealed a bimodal distribution of the sparteine metabolic ratio and showed the existence of two