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Oxidation of N-Methyl-1,2,3,4-Tetrahydroisoquinoline into the N-Methyl-Isoquinolinium Ion by Monoamine Oxidase

โœ Scribed by Makoto Naoi; Sadao Matsuura; Hasan Parvez; Tsutomu Takahashi; Yoko Hirata; Masayasu Minami; Toshiharu Nagatsu


Book ID
111175301
Publisher
John Wiley and Sons
Year
1989
Tongue
English
Weight
325 KB
Volume
52
Category
Article
ISSN
0022-3042

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A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-earboxylic acid derivatives from ot,tx'-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.