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Oxidation of cardiac myoglobin in vivo by sodium nitrite or hydroxylamine

✍ Scribed by John W. Nichols; Lavern J. Weber


Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
504 KB
Volume
63
Category
Article
ISSN
0340-5761

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Oxidative carbon-carbon bond cleavage of N-alkoxycarbonylated cyclic amines was accomplished by NaNO 2 in TFA to afford x-amino carboxylic acid in high yield. Optically active 3-hydroxypiperidine derivatives and 3-pipecolinate were converted to enantiomerically pure (R)-4-amino-3-hydroxybutanoic aci