Oxidation of acetaldehyde and presence of aldehyde dehydrogenase in rat erythrocytes
β Scribed by Henry Weiner; Nancy Truesdale-Mahoney; Anthony J. Pelletier
- Book ID
- 113219439
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 376 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0091-3057
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A method has been developed for the determination of low concentrations of acetaldehyde in rat blood. The method involves extraction of blood in perchloric acid followed by a fluorimetric determination of acetaldehyde in neutralized extracts by the use of a low K(m) aldehyde dehydrogenase isolated f
The hepatic oxidation of ethanol has been demonstrated to cause peroxidation of cellular membranes, resulting in the production of aldehydes that are substrates for hepatic aldehyde dehydrogenases. It was the purpose of this study to evaluate the cooxidation of the lipid peroxidation product, truns-