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Oxidation of 5-hydroxytryptamine and 5,7-dihydroxytryptamine. A new oxidation pathway and formation of a novel neurotoxin

โœ Scribed by Wrona, Monika Z.; Lemordant, Daniel; Lin, L.; Blank, C. LeRoy; Dryhurst, Glenn


Book ID
127032180
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
921 KB
Volume
29
Category
Article
ISSN
0022-2623

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Spectral data provide the first evidence that lactoperoxidase, a model enzyme for most mammalian peroxidases, catalyzed the one-electron oxidation and/or peroxidation of 5,7-dihydroxytryptamine. This process correlates with the production of superoxide radicals as is evident from the observed inhibi