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Oxidation of 4-hydroxynonenal in rat brain slices

✍ Scribed by Tonya Murphy; Venkataraman Amarnath; Matthew J Picklo


Book ID
114008948
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
121 KB
Volume
143-144
Category
Article
ISSN
0009-2797

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✍ Gabriella Leonarduzzi; Elena Chiarpotto; Fiorella Biasi; Giuseppe Poli πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 123 KB

4-Hydroxynonenal (HNE) is by far the most investigated aldehydic end-product of oxidative breakdown of membrane n-6 polyunsaturated fatty acids. Its potential involvement in the pathogenesis of atherosclerosis has been corroborated by its consistent detection in both oxidized LDL and fibrotic plaque