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Oxidant-mediated proteolytic activation of Ca2+-ATPase in microsomes of pulmonary smooth muscle

โœ Scribed by Salil K. Ghosh; Tapati Chakraborti; John R. Michael; Sajal Chakraborti


Book ID
115932421
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
378 KB
Volume
387
Category
Article
ISSN
0014-5793

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We sought to investigate the mechanism(s) by which the oxidant H2O2 stimulates Ca2+ release from mitochondria of bovine pulmonary vascular smooth muscle tissue and to test the hypothesis that hydroxyl radical is involved in this phenomenon. Treatment of the smooth muscle tissue with 1 mM H2O2 dramat