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Matrix Metalloproteinase-2-Mediated Inhibition of Na + -Dependent Ca2 + Uptake by Superoxide Radicals (O2. - ) in Microsomes of Pulmonary Smooth Muscle

โœ Scribed by Amritlal Mandal; Tapati Chakraborti; Sudip Das; Biswarup Ghosh; Amarnath Ghosh; Sajal Chakraborti


Book ID
111741596
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
877 KB
Volume
56
Category
Article
ISSN
1521-6543

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We sought to investigate the mechanism(s) by which the oxidant H2O2 stimulates Ca2+ release from mitochondria of bovine pulmonary vascular smooth muscle tissue and to test the hypothesis that hydroxyl radical is involved in this phenomenon. Treatment of the smooth muscle tissue with 1 mM H2O2 dramat