Oxazoline N-Oxide-Mediated [2+3] Cycloadditions: New Access to Quaternary Asymmetric Centres

✍ Scribed by Stéphane Collon; Cyrille Kouklovsky; Yves Langlois

• Book ID: 101352804
• Publisher: John Wiley and Sons
• Year: 2002
• Tongue: English
• Weight: 138 KB
• Volume: 2002
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/1099-0690(200211)2002:21<3566::aid-ejoc3566>3.0.co;2-f

✦ Synopsis

Cycloadditions between camphor-derived oxazoline N-oxide 1 and dipolarophiles 5 or 8 afforded adducts 6 and 9, respectively, with almost complete regio-and stereoselectivity depending on the substitution patterns of the dipolarophiles.