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Oxazolidinone to succinamide: a novel rearrangement reaction

✍ Scribed by Menyan Cheng; Biswanath De; Christopher T. Wahl; Neil G. Almstead; Michael G. Natchus; Stanislaw Pikul

Book ID
104261951
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
155 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis

During the course of an investigative work with a monosubstituted succinic acid half-ester tethered to a chiral oxazolidinone, an unexpected disubstituted succinimide was obtained with a high degree of stereoselectivity as the major product. Subsequent investigative work confirmed the structure and further defined the scope of this rearrangement reaction.

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