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Oxazepines and Thiazepines, XXVII: Chemical Transformations of 2,3-Dihydro-2-phenyl-1,4-benzoxazepin-5(4H)-one

✍ Scribed by Albert Lévai; Zoltán Bálint


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
280 KB
Volume
326
Category
Article
ISSN
0365-6233

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A Facile Synthesis of Substituted 1,4-Be
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5(4H)-ones / 2-Chloro-N-cyanomethyl-N-methylnicotinamide / Aromatic nucleophilic substitution A new synthesis of pyrido[3,2-f][1,4]thiazepine derivatives 3 starting with 2-chloronicotinic acid (1), methylaminoacetonitrile hydrochloride and carbon disulfide is described. As proved by a crystal struct