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Oxaspiropentane. A rapid route to cyclobutanone

✍ Scribed by Sala�n, J. R.; Conia, J. M.


Book ID
120594706
Publisher
Royal Society of Chemistry
Year
1971
Weight
99 KB
Volume
0
Category
Article
ISSN
0577-6171

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An efficient route to 3-(hydroxymethyl)cyclobutanone acetals via a [2+2] cycloaddition reaction is reported. The dramatic effect of different diol acetals on benzyl deprotection is discussed. Efficient synthesis of two synthetically useful intermediates, 3-methylenecyclobutanone acetal and 3-(bromom