An efficient route to 3-substituted cycl
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George W. Kabalka; Min-Liang Yao
📂
Article
📅
2003
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Elsevier Science
🌐
French
⚖ 126 KB
An efficient route to 3-(hydroxymethyl)cyclobutanone acetals via a [2+2] cycloaddition reaction is reported. The dramatic effect of different diol acetals on benzyl deprotection is discussed. Efficient synthesis of two synthetically useful intermediates, 3-methylenecyclobutanone acetal and 3-(bromom