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OX40 Promotes Bcl-xL and Bcl-2 Expression and Is Essential for Long-Term Survival of CD4 T Cells

✍ Scribed by Paul R Rogers; Jianxun Song; Irene Gramaglia; Nigel Killeen; Michael Croft

Book ID
117723102
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
407 KB
Volume
15
Category
Article
ISSN
1074-7613

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## Abstract Defects in apoptosis have been implicated in chemoresistance of colon cancer cells. We report here the ability to resist to 5‐fluorouracil‐induced apoptosis of 8 colon cancer cell lines differing in __p53__ and __bax__ status: p53^βˆ’/0^bax^+/+^ for TC7, SW480, HT‐29; p53^+/+^bax^βˆ’/βˆ’^ for