𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Overview of vector design for mammalian gene expression

✍ Scribed by Kaufman, R. J. (author)

Book ID
111640143
Publisher
Humana Press
Year
2000
Tongue
English
Weight
110 KB
Volume
16
Category
Article
ISSN
1073-6085

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Silencing of gene expression: implicatio
Silencing of gene expression: implications for design of retrovirus vectors
✍ Dylan Pannell; James Ellis πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 182 KB

## Abstract Transcriptional silencing of retroviruses poses a major obstacle to their use as gene therapy vectors. Silencing is most pronounced in stem cells which are desirable targets for therapeutic gene delivery. Many vector designs combat silencing through __cis__‐modifications of retroviral v

pTRIDENT, a novel vector family for tric
pTRIDENT, a novel vector family for tricistronic gene expression in mammalian cells
✍ Martin Fussenegger; Xenia Mazur; James E. Bailey πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 280 KB

We constructed tricistronic expression vectors for the simultaneous and coordinated expression of three independent genes in mammalian cells. One single promoter allows high level and, in some vectors, adjustable transcription of all three cistrons. Whereas the first cistron is translated in a cap-d

Inducible vectors for expression in mamm
Inducible vectors for expression in mammalian cells
✍ Geoffrey T. Yarranton πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 English βš– 594 KB

The most recent developments in mammalian cell inducible expression systems have involved the use of bacterial gene control elements and viral transactivator proteins. The combination of hybrid viral transactivator and bacterial repressor proteins, and simple chemical inducers can provide induction