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Overlapping and specific patterns of GDNF, c-ret and GFRα mRNA expression in the developing chicken retina

✍ Scribed by Miriam Karlsson; Niclas Lindqvist; Raquel Mayordomo; Finn Hallböök


Book ID
118602408
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
413 KB
Volume
114
Category
Article
ISSN
0925-4773

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RET is a receptor tyrosine kinase expressed in neuroendocrine cells and in tumors of these cell types. RET activation may be mediated by a ligand complex comprising glial cell line-derived neurotrophic factor (GDNF) and GDNF family receptor alpha-1 (GFR␣-1). Activating RET mutations are found in the