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Overexpression of α-methylacyl-CoA racemase is associated with CTNNB1 mutations in hepatocellular carcinomas

✍ Scribed by Shigeki Sekine; Reiko Ogawa; Hidenori Ojima; Yae Kanai

Book ID
108781041
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
1020 KB
Volume
58
Category
Article
ISSN
0309-0167

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## Abstract ## BACKGROUND Inhibitor of differentiation/DNA binding protein 1 (Id‐1) plays a pivotal role in the regulation of cell proliferation and carcinogenesis via inhibiting basic helix‐loop‐helix (HLH) transcription factors. Recently, Id‐1 was found to repress p16 in tumorous tissue specimen