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Overexpression of the novel oncogene SALL4 and activation of the Wnt/β-catenin pathway in myelodysplastic syndromes

✍ Scribed by Xiao Shuai; Daobin Zhou; Ti Shen; Yongji Wu; Jieping Zhang; Xuan Wang; Qian Li

Book ID
113513593
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
521 KB
Volume
194
Category
Article
ISSN
0165-4608

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## Abstract The WNT/β‐catenin pathway is involved in numerous human cancers. Mutations of the __CTNNB1__ (β‐catenin) gene have also been detected in a subset of pediatric Wilms tumors, but the target genes of the deregulated WNT/β‐catenin pathway in these tumors have yet to be identified. To compar