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Overexpression of p16INK4 is a reliable marker of human papillomavirus–induced oral high-grade squamous dysplasia

✍ Scribed by Larry L. Cunningham Jr; Giulia M. Pagano; Mengtao Li; Rahul Tandon; Stephen W. Holm; Dean K. White; Subodh M. Lele

Book ID
116941418
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
211 KB
Volume
102
Category
Article
ISSN
1528-395X

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## Abstract ## BACKGROUND The primary goal of this study was to compare the clinical performance of an optimized and rigorously controlled immunocytochemical (ICC) assay for p16^INK4a^ to high‐risk (HR) human papillomavirus (HPV) detection by polymerase chain reaction (PCR) as diagnostic adjuncts