Citrus fruits are high in naringin, which has a beneficial effect on cardiovascular diseases. However, the matrix metalloproteinase-9 (MMP-9) regulation involved in cell migration and invasion remains to be identified. Naringin inhibited tumor necrosis factor-alpha (TNF-alpha)-induced expression of
β¦ LIBER β¦
Overexpression of membrane sialic acid-specific sialidase Neu3 inhibits matrix metalloproteinase-9 expression in vascular smooth muscle cells
β Scribed by Sung-Kwon Moon; Seung-Hak Cho; Kyung-Woon Kim; Jae Heung Jeon; Jeong-Heon Ko; Bo Yeon Kim; Cheorl-Ho Kim
- Book ID
- 116294598
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 201 KB
- Volume
- 356
- Category
- Article
- ISSN
- 0006-291X
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## Abstract The expression of matrix metalloproteinaseβ9 (MMPβ9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMPβ9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor