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Overexpression of Kelch domain containing-2 (mKlhdc2) inhibits differentiation and directed migration of C2C12 myoblasts

✍ Scribed by Petra Neuhaus; Benjamin Jaschinsky; Sebastian Schneider; Herbert Neuhaus; Annelies Wolter; Henning Ebelt; Thomas Braun


Book ID
113955545
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
668 KB
Volume
312
Category
Article
ISSN
0014-4827

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✍ Yusuke Ono; Hiroomi Sensui; Yuzuru Sakamoto; Ryoichi Nagatomi πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 227 KB

## Abstract We analyzed the role of Hypoxia‐inducible factor (HIF)‐1Ξ± in myoblast differentiation by examining the expression and regulation of HIF‐1Ξ± in proliferating and differentiating C2C12 myoblast, and by knocking down HIF‐1Ξ± of C2C12 myoblasts with small interfering RNA (siRNA), given that H