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Overexpression of cytosolic sialidase Neu2 induces myoblast differentiation in C2C12 cells

✍ Scribed by A. Fanzani; R. Giuliani; F. Colombo; D. Zizioli; M. Presta; A. Preti; S. Marchesini

Book ID
117105596
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
351 KB
Volume
547
Category
Article
ISSN
0014-5793

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## Abstract Addition of nordihydroguaiaretic acid (NDGA) to the differentiation medium of C2C12 mouse myoblast cells caused severe inhibition of the formation of myotubes and suppressed differentiation‐dependent elevation in the levels of the creatine kinase M isozyme (CKM). Under these conditions,