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Overexpression of HER-2/neu is not a risk factor in ovarian clear cell adenocarcinoma

✍ Scribed by Hiroshi Tanabe; Hiroshi Nishii; Akihiko Sakata; Keitaro Suzuki; Yukiko Mori; Hideo Shinozaki; Akihiko Watanabe; Kazuhiko Ochiai; Makoto Yasuda; Tadao Tanaka


Book ID
113959387
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
156 KB
Volume
94
Category
Article
ISSN
0090-8258

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__