Overexpression of hepatocyte growth factor/scatter factor promotes vascularization and granulation tissue formation in vivo
β Scribed by Mitsuo Toyoda; Hisashi Takayama; Norio Horiguchi; Toshiyuki Otsuka; Toshio Fukusato; Glenn Merlino; Hitoshi Takagi; Masatomo Mori
- Book ID
- 117103644
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 716 KB
- Volume
- 509
- Category
- Article
- ISSN
- 0014-5793
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Angiogenesis is a possible target in the treatment of human gliomas. To evaluate the role of 3 growth factors, vascular endothelial growth factor (VEGF), hepatocyte growth factor/scatter factor (HGF/SF) and basic fibroblast growth factor (bFGF), in the angiogenic cascade, we determined their levels
## Abstract ## Objective Connective tissue growth factor (CTGF) is a cysteineβrich secreted matricellular protein involved in wound healing and tissue repair. Enhanced and prolonged expression of CTGF has been associated with tissue fibrosis in humans. However, questions remain as to whether CTGF