Overexpression of human insulin-like growth factor-I promotes new tissue formation in an ex vivo model of articular chondrocyte transplantation

Overexpression of human fibroblast growt

Overexpression of human fibroblast growth factor 2 stimulates cell proliferation in an ex vivo model of articular chondrocyte transplantation

✍ Henning Madry; Greg Emkey; David Zurakowski; Stephen B Trippel 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 230 KB

## Background: Genetically engineered chondrocytes could be used to enhance cartilage repair. fibroblast growth factor 2 (fgf-2) is a mitogen for chondrocytes and may be a candidate for gene transfer approaches to stimulate chondrocyte proliferation. in the present study, we tested the hypothesis t