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Overexpression of glutamine:fructose-6-phosphate-amidotransferase induces transforming growth factor-β1 synthesis in NIH-3T3 fibroblasts

✍ Scribed by Cora Weigert; Katrin Brodbeck; Rainer Lehmann; Hans U. Häring; Erwin D. Schleicher


Book ID
117102621
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
172 KB
Volume
488
Category
Article
ISSN
0014-5793

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## Abstract Transforming growth factor‐beta (TGF‐beta), a potent cytokine, modulates a wide variety of biological responses. Among its actions, TGF‐beta can augment prostaglandin synthesis in several cell types. Although TGF‐beta alone has no effect on prostaglandin production in Swiss 3T3 cells, w