๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Overexpression of [gamma ]-glutamylcysteine synthetase in human malignant mesothelioma

โœ Scribed by Kristiina J[auml ]rvinen; Ylermi Soini; Katriina Kahlos; Vuokko L. Kinnula


Book ID
117818615
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
364 KB
Volume
33
Category
Article
ISSN
1532-8392

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Co-ordinated over-expression of the MRP
โœ Besim Ogretmen; Hamid R. Bahadori; Mary D. McCauley; Alice Boylan; Mark R. Green ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 84 KB ๐Ÿ‘ 1 views

While human malignant mesothelioma is extremely resistant to chemotherapy, its intrinsic resistance mechanisms remain largely unknown. In this study, we used normal human mesothelial cells and 5 human mesothelioma cell lines not previously exposed to chemotherapeutic agents to demonstrate that the m

Co-expression of gamma-glutamylcysteine
โœ Tetsuya Iida; Eri Mori; Katsuharu Mori; Shinji Goto; Yoshishige Urata; Mikio Oka ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 178 KB

Glutathione (โฅ-glutamylcysteinyl glycine, GSH) is believed to be important in the acquisition of resistance to anti-cancer drugs such as cisplatin (CDDP) and doxorubicin (DOX). โฅ-Glutamylcysteine synthetase (โฅ-GCS) is a key enzyme for maintaining intracellular GSH levels; it is composed of a catalyt