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Overexpression of Cyclin-dependent Kinase-activating CDC25B Phosphatase in Human Gastric Carcinomas

✍ Scribed by Kudo, Yasusei ;Yasui, Wataru ;Ue, Teruyoshi ;Yamamoto, Soichiro ;Yokozaki, Hiroshi ;Nikai, Hiromasa ;Tahara, Eiichi


Book ID
108581346
Publisher
Wiley (Blackwell Publishing)
Year
1997
Tongue
English
Weight
486 KB
Volume
88
Category
Article
ISSN
0910-5050

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We examined the expression of p34 cdcz and its kinase activity in human gastric and colonic carcinoma cell lines and carcinoma tissues and studied its relation with a tumor-suppressor gene product, p53. All the gastric and colonic cancer cell lines expressed p34'dC2 and showed its kinase activity at