## Abstract __Cyclin D1__ is frequently overexpressed in human neoplasias by gene rearrangement and amplification. In addition, Ras, PTEN and Ξ²βcatenin appear to modulate cyclin D1 levels. Since the causes of cyclin D1 overexpression are poorly understood in EC, we investigated whether or not this
Overexpression of cyclin D1 in nonmelanocytic skin cancer
β Scribed by S.-B. Liang; M. Furihata; T. Takeuchi; J. Iwata; B.-K. Chen; H. Sinobe; Y. Ohtsuki
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 778 KB
- Volume
- 436
- Category
- Article
- ISSN
- 1432-2307
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## BACKGROUND. Hypopharyngeal squamous cell carcinomas (HPCS) are associated with an extremely poor prognosis. Generally, conventional clinicopathologic factors have only limited value as prognostic factors for this malignancy. It is therefore clinically important to identify new prognostic factor
The biological behaviour of urinary bladder neoplasms cannot be adequately predicted by histological criteria alone. Cyclin D1 is a cell-cycle regulating protein known to be overexpressed in a proportion of bladder carcinomas. To evaluate the prognostic significance of cyclin D1 expression and its r
Expression of cyclins D1 and D2, as well as cyclin-dependent kinase 4 (cdk4), was investigated by means of immunohistochemistry in 455 gastric cancer cases. Additional western blotting was performed for four breast cancer and four gastric cancer cell lines and 35 fresh frozen gastric cancer samples,