Acute promyelocytic leukemia (APL) is characterized by the t(15;17) cytogenetic abnormality leading to the expression of two fusion genes, PML/RARA and RARA/PML, and by its sensitivity to all-trans retinoic acid (ATRA) differentiating treatment. Rare APL cases lacking the t(15;17) have been describe
β¦ LIBER β¦
Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells
β Scribed by Rania T. Awwad; Khanh Do; Holly Stevenson; Sidney W. Fu; Francesco Lo-Coco; Maura Costello; Cassandra L. Campbell; Patricia E. Berg
- Book ID
- 105989049
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 263 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0939-5555
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