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Overexpression and functional alterations of the EphA2 tyrosine kinase in cancer

โœ Scribed by Michael S. Kinch; Kelly Carles-Kinch


Book ID
110421656
Publisher
Springer
Year
2003
Tongue
English
Weight
259 KB
Volume
20
Category
Article
ISSN
0262-0898

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Estrogen and Myc negatively regulate exp
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## Abstract Estrogen receptor and cโ€Myc are frequently overexpressed during breast cancer progression but are downregulated in many aggressive forms of the disease. High levels of the EphA2 tyrosine kinase are consistently found in the most aggressive breast cancer cells, and EphA2 overexpression c