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Overexpression and Activation of the RON Receptor Tyrosine Kinase in a Panel of Human Colorectal Carcinoma Cell Lines

✍ Scribed by Yi-Qing Chen; Yong-Qing Zhou; Debora Angeloni; Avrom L. Kurtz; Xiao-Zhi Qiang; Ming-Hai Wang


Book ID
115603808
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
315 KB
Volume
261
Category
Article
ISSN
0014-4827

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Phosphotyrosine (P-Tyr) antibodies have been used to identify the phosphorylated forms of growth factor receptors and oncogene-coded tyrosine kinases. Western blot analysis of a gastric carcinoma cell line with P-Tyr antibodies revealed a tyrosine-phosphorylated protein of M, 145,000 (P145). In addi