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Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells

✍ Scribed by Song, Lanxi; Turkson, James; Karras, James G; Jove, Richard; Haura, Eric B


Book ID
110067583
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
375 KB
Volume
22
Category
Article
ISSN
0950-9232

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## Abstract ZD6474 is a vascular endothelial growth factor receptor (VEGFR) and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor. The present study was undertaken to investigate the direct antiproliferative effect of ZD6474 on human nasopharyngeal carcinoma (NPC) __in vitro__ and t