Overcoming intrinsic diastereoselection using polyleucine as a chiral epoxidation catalyst

✍ Scribed by Peter C. Ray; Stanley M. Roberts

• Book ID: 104260626
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 239 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)02689-6

✦ Synopsis

The use of polyleucine in the diastereoselective, catalyst-controlled epoxidation of enantiomerically pure 7-heterosubstituted-ct,13-unsaturated ketones (1), to yield the corresponding ct,13-epoxy-)',8-(isopropylidene)dioxy carbonyl compounds, is described.