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Ovarian cancer patient with germline mutations in both BRCA1 and NBN genes

โœ Scribed by Nathalia V. Porhanova; Anna P. Sokolenko; Nathalia Yu. Sherina; Daria N. Ponomariova; Nathalia N. Tkachenko; Dmitry E. Matsko; Evgeny N. Imyanitov


Book ID
113513399
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
236 KB
Volume
186
Category
Article
ISSN
0165-4608

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Germline mutations in the BRCA1 and BRCA
โœ A. Esra Manguoวงlu; Gรผven Lรผleci; Tayfun ร–zรงelik; Taner ร‡olak; Hagit Schayek; Mus ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 47 KB ๐Ÿ‘ 2 views

In this study we genotyped Turkish breast/ovarian cancer patients for BRCA1/BRCA2 mutations: protein truncation test (PTT) for exon 11 BRCA1 of and, multiplex PCR and denaturing gradient gel electrophoresis (DGGE) for BRCA2, complemented by DNA sequencing. In addition, a modified restriction assay w