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Ouabain-resistant non-small-cell lung-cancer cell line shows collateral sensitivity to cis-diamminedichloroplatinum(II) (CDDP)

Book ID
122761570
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
145 KB
Volume
11
Category
Article
ISSN
0169-5002

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Ouabain-resistant non-small-cell lung-ca
Ouabain-resistant non-small-cell lung-cancer CELL LINE SHOWS COLLATERAL SENSITIVITY TO cis-diamminedichloroplatinum(II) (CDDP)
โœ Tohru Ohmori; Kazuto Nishio; Sei Ohta; Naohiro Kubota; Mitsuru Adachi; Kazuhide ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 768 KB

We have reported that the cellular uptake of cis-diamminedichloroplatinum(ll) (CDDP) was inhibited by an Na+,K+adenosine triphosphatase (ATPase) inhibitor, ouabain, in a human non-small-cell lung-cancer cell line, PC-14, but not in its CDDP-resistant cell line, PC-I4/CDDP. ['HIOuabain binding of PC-