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Effect of proton pump inhibitor on cell growth and sensitivity to cis-diamminedichloroplatinum (II) in non-small cell lung cancer cell lines

Book ID
122440069
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
129 KB
Volume
13
Category
Article
ISSN
0169-5002

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We have reported that the cellular uptake of cis-diamminedichloroplatinum(ll) (CDDP) was inhibited by an Na+,K+adenosine triphosphatase (ATPase) inhibitor, ouabain, in a human non-small-cell lung-cancer cell line, PC-14, but not in its CDDP-resistant cell line, PC-I4/CDDP. ['HIOuabain binding of PC-