Osteoprotegerin inhibits osteoclast formation and bone resorbing activity in giant cell tumors of bone
β Scribed by G.J Atkins; S Bouralexis; D.R Haynes; S.E Graves; S.M Geary; A Evdokiou; A.C.W Zannettino; S Hay; D.M Findlay
- Book ID
- 117807309
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 747 KB
- Volume
- 28
- Category
- Article
- ISSN
- 8756-3282
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## Abstract The present study was performed to examine the effect of the high concentration of extracellular calcium ([Ca^2+^]~e~) on osteoclastβlike cell formation and boneβresorbing activity in the presence or absence of osteoblasts. High [Ca^2+^]~e~ (3 and 5 mM) significantly stimulated osteocla
Prostaglandin E, (PGE,) is an important local regulator in bone. The present study was performed to investigate the effect of PGE, on osteoclast-like cell formation and bone-resorbing activity of mature osteoclasts in the presence or absence of osteoblasts. PGE, ( M) significantly stimulated osteocl