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Osteopontin Promotes Mesenchymal Stem Cell Migration and Lessens Cell Stiffness via Integrin β1, FAK, and ERK Pathways

✍ Scribed by Zou, Chengyu; Luo, Qing; Qin, Jian; Shi, Yisong; Yang, Li; Ju, Bingfeng; Song, Guanbin


Book ID
120074310
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
635 KB
Volume
65
Category
Article
ISSN
1085-9195

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## Abstract Tumor malignancy is associated with several features such as proliferation ability and frequency of metastasis. Osteopontin (OPN), which abundantly expressed in bone matrix, is involved in cell adhesion, migration, invasion and proliferation via interaction with its receptor, that is, α