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Osteopontin increases heme oxygenase-1 expression and subsequently induces cell migration and invasion in glioma cells

✍ Scribed by Lu, D.-Y.; Yeh, W.-L.; Huang, S.-M.; Tang, C.-H.; Lin, H.-Y.; Chou, S.-J.

Book ID
119970079
Publisher
Duke University Press
Year
2012
Tongue
English
Weight
550 KB
Volume
14
Category
Article
ISSN
1522-8517

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Heme oxygenase (HO) catalyzes the conversion of heme into biliverdin, iron, and carbon monoxide (CO). Two isoforms of HO have been identified: the inducible HO-1 and the constitutive HO-2. CO, like nitric oxide, is an endogenous vasodilator that could contribute to modulation of systemic and local v