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HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells

✍ Scribed by Tahereh Ghaziani; Ying Shan; Richard W. Lambrecht; Susan E. Donohue; Thomas Pietschmann; Ralf Bartenschlager; Herbert L. Bonkovsky


Book ID
116651027
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
178 KB
Volume
45
Category
Article
ISSN
0168-8278

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## Abstract We developed a retrovirus‐mediated human __heme oxygenase‐1__ (__HO‐1__) gene expression system and assessed the impact of heme on the inducibility of the __HO‐1__ gene in rat lung microvessel (RLMV) endothelial cells and in newborn Sprague‐Dawley (SD) rats. Overexpression of the __HO‐1