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Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells

✍ Scribed by Shinohara, Mari L; Lu, Linrong; Bu, Jing; Werneck, Miriam B F; Kobayashi, Koichi S; Glimcher, Laurie H; Cantor, Harvey

Book ID: 109923236
Publisher: Nature Publishing Group
Year: 2006
Tongue: English
Weight: 349 KB
Volume: 7
Category: Article
ISSN: 1529-2908
DOI: 10.1038/ni1327

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## Abstract ## Objective To investigate the release of interferon‐α (IFNα)–inducing material by necrotic or apoptotic cells, its properties, and the necessity of autoantibodies from systemic lupus erythematosus (SLE) patients for the interferogenic activity. ## Methods U937 monocytic leukemia ce