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Expression of the markers BDCA-2 and BDCA-4 and production of interferon-α by plasmacytoid dendritic cells in systemic lupus erythematosus

✍ Scribed by Stina Blomberg; Maija-Leena Eloranta; Mattias Magnusson; Gunnar V. Alm; Lars Rönnblom

Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 118 KB
Volume: 48
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.11225

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## Abstract ## Objective To investigate the release of interferon‐α (IFNα)–inducing material by necrotic or apoptotic cells, its properties, and the necessity of autoantibodies from systemic lupus erythematosus (SLE) patients for the interferogenic activity. ## Methods U937 monocytic leukemia ce