Osteogenic sarcoma following Hodgkin's disease
β Scribed by Daniel Niebrugge; Carlos Monzon; Michael C. Perry; Nasrollah Hakami
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 266 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
The cases of two children who developed osteogenic sarcoma of the distal femur following prolonged remission of Hodgkin's disease are reported. These cases are unique in that the sarcoma developed in an area not previously irradiated. This occurrence suggests the possibility of genetic susceptibility to primary cancers in certain individuals, although prior chemotherapy may have contributed to this occurrence.
π SIMILAR VOLUMES
Gonadal function was assessed in 101 postpubertal subjects after chemotherapy for childhood Hodgkin's disease. All had received ChlVPP (chlorambucil, vinblastine, procarbazine, and prednisolone) chemotherapy alone, with no radiotherapy below the diaphragm. Go- nadotropin levels were available in 46