Hodgkin's disease (HD) has long been suspected to have an infectious precursor, and indirect evidence has implicated Epstein-Barr virus (EBV), a ubiquitous herpesvirus, as a causal agent. Recent molecular studies using EBER in situ hybridization or latency membrane protein-1 (LMP-1) immunohistochemi
Epstein-barr virus-associated Hodgkin's disease following renal transplantation
✍ Scribed by Arnaud Jaccard; Jean-François Emile; Fabien Metivier; Jean-Pierre Clauvel; Marie-Françoise d'Agay
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 168 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0361-8609
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Epstein-Barr virus (EBV) has been frequently documented in the putative neoplastic Hodgkin-Reed-Sternberg (HRS) cells, in lymph nodes from patients with Hodgkin's disease (HD). This association varies in different geographic areas and between industrialized and developing countries, as does the epid
## Several lines of evidence suggest that the Epstein-Barr virus (EBV) is an important factor in the pathogenesis of Hodgkin's disease (HD). This Editorial focuses on two pathogenic mechanisms probably influenced by the presence of EBV in the Hodgkin and Reed-Sternberg (H-RS) cells: resistance of th
## BACKGROUND. The association of Epstein-Barr virus (EBV) with Hodgkin's disease (HD) is intimately related to socioeconomic status. The proportion of HD patients with EBV is high in developing countries but low in developed countries. The aim of this study was to delineate the association of EBV