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Osteoclast Differentiation Requires Ascorbic Acid

✍ Scribed by Ashraf A. Ragab; Sandra A. Lavish; Michael A. Banks; Victor M. Goldberg; Edward M. Greenfield


Book ID
111486347
Publisher
American Society for Bone and Mineral Research
Year
1998
Tongue
English
Weight
323 KB
Volume
13
Category
Article
ISSN
0884-0431

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## Abstract Based on our earlier observation that caspase‐3 is present in osteoclasts that are not undergoing apoptosis, we investigated the role of this protein in the differentiation of primary osteoclasts and RAW264.7 cells (Szymczyk KH, et al., 2005, Caspase‐3 activity is necessary for RANKL‐in