Implant wear induces inflammation, but n
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Weiping Ren; Bin Wu; Xin Peng; Jing Hua; Hsiao-Nan Hao; Paul H. Wooley
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Article
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2006
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Elsevier Science
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English
β 698 KB
## Abstract Signaling of RANK (receptor activator of nuclear factor kappa B) through its ligand RANKL appears critical in osteolysis associated with aseptic loosening (AL). The purpose of this study was to investigate the role of RANK in a murine osteolysis model developed in RANK knockout (RANK^β/