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Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor

✍ Scribed by N Udagawa; N Takahashi; E Jimi; K Matsuzaki; T Tsurukai; K Itoh; N Nakagawa; H Yasuda; M Goto; E Tsuda; K Higashio; M.T Gillespie; T.J Martin; T Suda

Book ID: 117808983
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 562 KB
Volume: 25
Category: Article
ISSN: 8756-3282
DOI: 10.1016/s8756-3282(99)00210-0

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## Abstract Mouse bone marrow‐derived macrophages proliferate in the presence of macrophage colony‐stimulating factor (M‐CSF), granulocyte‐macrophage colony‐stimulating factor, or IL‐3, but undergo apoptosis in their absence. Inhibition of extracellular signal‐regulated kinases (ERK)‐1/2 blocks gro