Osseointegration in cortical sheep bone of calcium phosphate implants evaluated by PIXE method and histology

✍ Scribed by Braye, F. ;Weber, G. ;Irigaray, J. L. ;Frayssinet, P.

• Publisher: John Wiley and Sons
• Year: 1997
• Tongue: English
• Weight: 574 KB
• Volume: 36
• Category: Article
• ISSN: 0021-9304
• DOI: 10.1002/(sici)1097-4636(19970905)36:3<315::aid-jbm6>3.0.co;2-h

✦ Synopsis

Osseointegration of porous calcium phosphate the osseointegration index. Two regions of the curves were ceramics evolves in several stages once implanted. Histologic identified for each element characterizing either the bone analysis has often been used to evaluate the mechanism of tissue or the ceramic. Zinc and strontium present in the bone integration of this material. Histologic parameters can be tissue but absent from the ceramics appeared after the 8th completed by physical analysis to obtain a semiquantitative and the 12th implantation weeks, respectively. Iron present evaluation of the osseointegration process. The histologic in the implant decreased with time, and calcium and phosobservation of hydroxyapatite (HA)-ceramic-containing phorus contents tended to be the same at the end of the bone sections was associated with proton-induced X-ray implantation period in both curve regions. Histologic obseremission (PIXE) analysis and the results obtained by both vation showed that immature bone invaded the pores of the methods were compared. Porous HA-ceramic cylinders were outer layer of the ceramic as early as 2 weeks after implantaimplanted in cortical bone of sheep femurs for periods rang-tion. Ceramics were totally osseointegrated 20 weeks after ing from 2 to 36 weeks. Thick sections of the implant con-implantation. Osseointegration was apparently still evolving taining bone were made at the end of the implantation period.

as judged by the PIXE method when histologic integration A scanning line with two proton impacts 0.5 mm apart was was considered complete.