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Oseltamivir Resistance during Treatment of Influenza A (H5N1) Infection

✍ Scribed by de Jong, Menno D.; Thanh, Tran Tan; Khanh, Truong Huu; Hien, Vo Minh; Smith, Gavin J.D.; Chau, Nguyen Vinh; Cam, Bach Van; Qui, Phan Tu; Ha, Do Quang; Guan, Yi; Peiris, J.S. Malik; Hien, Tran Tinh; Farrar, Jeremy

Book ID
120828095
Publisher
Massachusetts Medical Society
Year
2005
Tongue
English
Weight
759 KB
Volume
353
Category
Article
ISSN
0096-6762

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## Abstract Influenza A (H5N1) virus is one of the world's greatest pandemic threats. Neuraminidase (NA) inhibitors, oseltamivir and zanamivir, prevent the spread of influenza, but drug‐resistant viruses have reduced their effectiveness. Resistance depends on the binding properties of NA‐drug compl