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Computational investigation of oseltamivir resistance in influenza A (H5N1) virus

✍ Scribed by Karthick, V.; Ramanathan, K.

Book ID
120399606
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
554 KB
Volume
22
Category
Article
ISSN
1054-2523

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## Abstract Influenza A (H5N1) virus is one of the world's greatest pandemic threats. Neuraminidase (NA) inhibitors, oseltamivir and zanamivir, prevent the spread of influenza, but drug‐resistant viruses have reduced their effectiveness. Resistance depends on the binding properties of NA‐drug compl